Mutated EGFR-IN-3
Product Specifications
CAS Number
2375107-27-8
Target
EGFR
Related Pathways
Angiogenesis, Tyrosine Kinase/Adaptors, JAK/STAT signaling
Bioactivity
Mutated EGFR-IN-3 is a ATP-competitive and highly selective allosteric dibenzodiazepinone EGFR (L858R/T790M) and EGFR (L858R/T790M/C797S) inhibitor (IC50 of 12 nM and 13 nM, respectively.)
Smiles
O=C1C2=CC(OC3=CC=C(C=C3)N4CCN(C)CC4)=CC=C2NC5=CC=C(F)C=C5N1CC=6C=CC=CC6
Molecular Formula
C31H29FN4O2
Molecular Weight
508.59
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
K3330703 1.0 µg DNA
Gm3238 sgRNA CRISPR Lentivector (Mouse) (Target 2)
Sign In for Pricing
View Details RC220430L4V 200 µL
SLC43A3 (NM_017611) Human Tagged ORF Clone Lentiviral Particle
Sign In for Pricing
View Details