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Mutant IDH1-IN-2

Product Specifications

CAS Number

1429176-69-1

Target

Isocitrate Dehydrogenase (IDH)

Related Pathways

Metabolism

Purity

0.9988

Bioactivity

Mutant IDH1-IN-2 is an inhibitor of mutant Isocitrate dehydrogenase (IDH) proteins, with an IC50 of 16.6 nM in fluorescence biochemical assay and an IC50 of <22 nM in LS-MS biochemical assay.

Smiles

CC(C)[C@H]1COC(=O)N1c1ccnc(N[C@@H](C)c2ccc(CN3CCC(F)(F)CC3)cc2)n1

Molecular Formula

C24H31F2N5O2

Molecular Weight

459.53

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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