What is the catalog number for MRK-016?

The catalog number for MRK-016 is T12105.

What sizes are available for MRK-016?

MRK-016 is available in the following size(s): 1 mg, 5 mg, 1 mL - 10 mM (in DMSO), 10 mg, 25 mg, 50 mg.

How many pack sizes does MRK-016 come in?

MRK-016 is available in 6 different pack sizes.

MRK-016 is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures MRK-016?

MRK-016 is manufactured by Molfinity.

What is the estimated delivery time for MRK-016?

Estimated delivery time for MRK-016 is approximately 10 business day(s), depending on your location.

MRK-016

Product Specifications

CAS Number

342652-67-9

Target

GABA Receptor

Related Pathways

Membrane transporter/Ion channel, Neuroscience

Purity

0.9976

Bioactivity

MRK-016 is a selective GABAA α5 receptor inverse agonist/ negative allosteric modulator, (IC50=3 nM) with the advantages of being orally available and penetrating the blood-brain barrier.MRK-016 increases long time period potentiation (LTP) in mouse hippocampal slices, with memory-improvement, antidepressant, and pain-treating effects.