MMAF-OMe
Product Specifications
CAS Number
863971-12-4
Target
ADC Cytotoxin
Related Pathways
Antibody-drug Conjugate/ADC Related
Purity
0.9934
Bioactivity
MMAF-OMe (Monomethyl auristatin F methyl ester) is an antitubulin agent which inhibits several tumor cell lines with IC50s of 0.056 nM, 0.166 nM, 0.183 nM, and 0.449 nM for MDAMB435/5T4, MDAMB361DYT2, MDAMB468, and Raji (5T4-) cell lines, respectively. MMAF-Ome is also an ADC cytotoxin.
Smiles
CC[C@H](C)[C@@H]([C@@H](CC(=O)N1CCC[C@H]1[C@H](OC)[C@@H](C)C(=O)N[C@@H](Cc1ccccc1)C(=O)OC)OC)N(C)C(=O)[C@@H](NC(=O)[C@@H](NC)C(C)C)C(C)C
Molecular Formula
C40H67N5O8
Molecular Weight
745.99
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
More Discoveries
Explore Other Products
Browse additional items from our catalog
LS054936-100ug 100 µg
ARH3 (ADPRHL2) (NM_017825) Human Over-expression Lysate
Sign In for Pricing
View Details 
K0557703 1.0 µg DNA
CYTH3 sgRNA CRISPR Lentivector (Human) (Target 2)
Sign In for Pricing
View Details