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MK-8033 hydrochloride

Product Specifications

CAS Number

1283000-43-0

Target

C-Met/HGFR, Others

Related Pathways

Tyrosine Kinase/Adaptors, Others

Bioactivity

MK-8033 hydrochloride is an effective and orally active dual inhibitor of ATP competitive c-Met/Ron, with 1 nM for c-Met and 7nM for Ron IC50. MK-8033 hydrochloride has a high affinity for activated kinase conformation, and is suitable for the study of breast cancer, bladder cancer, and non-small cell lung cancer (NSCLC) .

Smiles

Cl.Cn1cc(cn1)-c1cnc2ccc3ccc(CS(=O)(=O)NCc4ccccn4)cc3c(=O)c2c1

Molecular Formula

C25H22ClN5O3S

Molecular Weight

507.99

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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