MK-8033 hydrochloride
Product Specifications
CAS Number
1283000-43-0
Target
C-Met/HGFR|||Others
Related Pathways
Tyrosine Kinase/Adaptors|||Others
Bioactivity
MK-8033 hydrochloride is an effective and orally active dual inhibitor of ATP competitive c-Met/Ron, with 1 nM for c-Met and 7nM for Ron IC50. MK-8033 hydrochloride has a high affinity for activated kinase conformation, and is suitable for the study of breast cancer, bladder cancer, and non-small cell lung cancer (NSCLC) .
Smiles
Cl.Cn1cc(cn1)-c1cnc2ccc3ccc(CS(=O)(=O)NCc4ccccn4)cc3c(=O)c2c1
Molecular Formula
C25H22ClN5O3S
Molecular Weight
507.99
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
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