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MK 0893

Product Specifications

CAS Number

870823-12-4

Target

Glucagon Receptor

Related Pathways

GPCR/G Protein

Purity

0.9879

Bioactivity

MK 0893 is a potent and selective Glucagon Receptor (GR) antagonist (IC50=6.6 nM) with competitive, reversible, high binding affinity and functional cAMP activity, which attenuates glucagon induced blood glucose elevation and reduces ambient glucose levels in acute and chronic mouse models.

Smiles

[C@@H](C)(N1C(=CC(=N1)C2=CC(Cl)=CC(Cl)=C2)C3=CC4=C(C=C3)C=C(OC)C=C4)C5=CC=C(C(NCCC(O)=O)=O)C=C5

Molecular Formula

C32H27Cl2N3O4

Molecular Weight

588.48

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Curated Selection

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