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MIV-247

Product Specifications

CAS Number

1352817-76-5

Target

Cysteine Protease

Related Pathways

Proteases/Proteasome

Purity

0.9931

Bioactivity

MIV-247 is a selective and potent inhibitor of cathepsin S (Kis 2.1, 4.2, and 7.5 nM for human, mouse, and wild monkey cathepsin S, respectively), which attenuates mechanical anomalies in preclinical models of neuropathic pain, and can be used to study cardiac muscle injury.

Smiles

N(C([C@H](CC1(F)CCCC1)NC(C(C)(F)F)=O)=O)C2(C(C(N)=O)=O)CCC2

Molecular Formula

C17H24F3N3O4

Molecular Weight

391.39

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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