MIV-247
Product Specifications
CAS Number
1352817-76-5
Target
Cysteine Protease
Related Pathways
Proteases/Proteasome
Purity
0.9931
Bioactivity
MIV-247 is a selective and potent inhibitor of cathepsin S (Kis 2.1, 4.2, and 7.5 nM for human, mouse, and wild monkey cathepsin S, respectively), which attenuates mechanical anomalies in preclinical models of neuropathic pain, and can be used to study cardiac muscle injury.
Smiles
N(C([C@H](CC1(F)CCCC1)NC(C(C)(F)F)=O)=O)C2(C(C(N)=O)=O)CCC2
Molecular Formula
C17H24F3N3O4
Molecular Weight
391.39
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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