Milademetan
Product Specifications
CAS Number
1398568-47-2
Target
MDM-2/p53, Mdm2, E1/E2/E3 Enzyme, Apoptosis
Related Pathways
Ubiquitination, Apoptosis
Purity
>99.99%
Bioactivity
Milademetan (DS-3032) is an orally active and potent MDM2 inhibitor with antitumor activity that induces G1 cell cycle arrest, senescence, and apoptosis.Milademetan is used in the study of acute myeloid leukemia and solid tumors.
Smiles
CC1(C)CCC2(CC1)N[C@H]([C@H](c1ccnc(Cl)c1F)[C@]21C(=O)Nc2cc(Cl)ccc12)C(=O)N[C@@H]1CC[C@H](OC1)C(N)=O
Molecular Formula
C30H34Cl2FN5O4
Molecular Weight
618.53
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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