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MI-1061

Product Specifications

CAS Number

1410737-34-6

Target

MDM-2/p53|||Apoptosis|||Mdm2|||E1/E2/E3 Enzyme

Related Pathways

Apoptosis|||Ubiquitination

Bioactivity

MI-1061 is a orally bioavailable inhibitor of MDM2 (MDM2-p53 interaction) (IC50=4.4 nM) .

Smiles

OC(=O)c1ccc(NC(=O)[C@@H]2NC3(CCCCC3)[C@]3([C@H]2c2cccc(Cl)c2F)C(=O)Nc2cc(Cl)ccc32)cc1

Molecular Formula

C30H26Cl2FN3O4

Molecular Weight

582.45

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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