MI-1061
Product Specifications
CAS Number
1410737-34-6
Target
MDM-2/p53|||Apoptosis|||Mdm2|||E1/E2/E3 Enzyme
Related Pathways
Apoptosis|||Ubiquitination
Bioactivity
MI-1061 is a orally bioavailable inhibitor of MDM2 (MDM2-p53 interaction) (IC50=4.4 nM) .
Smiles
OC(=O)c1ccc(NC(=O)[C@@H]2NC3(CCCCC3)[C@]3([C@H]2c2cccc(Cl)c2F)C(=O)Nc2cc(Cl)ccc32)cc1
Molecular Formula
C30H26Cl2FN3O4
Molecular Weight
582.45
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
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