Metarrestin
Product Specifications
CAS Number
1443414-10-5
Target
DNA/RNA Synthesis
Related Pathways
DNA Damage/DNA Repair, Cell Cycle/Checkpoint
Purity
0.9945
Bioactivity
Metarrestin (ML246) is a first-in-class perinucleolar compartment inhibitor with a favorable PK profile, which effectively suppresses metastasis. Metarrestin disrupts the nucleolar structure and inhibits RNA polymerase (Pol) I transcription, at least in part by interacting with the translation elongation factor eEF1A2.
Smiles
O[C@H]1CC[C@@H](CC1)n1cnc2n(Cc3ccccc3)c(c(-c3ccccc3)c2c1=N)-c1ccccc1
Molecular Formula
C31H30N4O
Molecular Weight
474.6
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
BP3423-50ug 50 µg
Recombinant Human Zinc finger CCCH-type antiviral protein 1/ZC3HAV1
Sign In for Pricing
View Details 
MBS2067157-01 0.1 mL
APC/CY7-Linked Polyclonal Antibody to Microfibrillar Associated Protein 2 (MFAP2)
Sign In for Pricing
View Details