PROTAC Mcl1 degrader-1
Product Specifications
CAS Number
2163793-38-0
Target
PROTACs, Bcl-2 Family
Related Pathways
PROTAC, Apoptosis
Purity
0.9874
Bioactivity
PROTAC Mcl1 degrader-1 is a Cereblon ligand-based targeted chimeric protein degrader (PROTAC), a selective Mcl-1 inhibitor. By hijacking the CRBN ubiquitin ligase to form a ternary complex with the target protein, it induces Mcl-1 ubiquitination. It can be used for cancer research.
Smiles
O=C1NC(=O)C(N2C(=O)C=3C=CC=C(NCCCCCCNC(=O)CCCCC(=O)NCCN4C(=O)C5=CC=CC=6C(SC7=CC=C(Br)C=C7)=CC=C(C4=O)C56)C3C2=O)CC1
Molecular Formula
C45H45BrN6O8S
Molecular Weight
909.84
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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