Mcl-1 inhibitor 3
Product Specifications
CAS Number
2376774-73-9
Target
Bcl-2 Family
Related Pathways
Apoptosis
Bioactivity
Mcl-1 inhibitor 3 shows good pharmacokinetic properties and excellent in vivo efficacy without toxicity.Mcl-1 inhibitor 3 is a highly potent and orally activate macrocyclic Mcl-1 inhibitor (Ki= 0.061 nM; IC50=19 nM in an OPM-2 cell viability assay) .
Smiles
[H][C@@]12CC[C@@]1([H])[C@@H](OCCN1CC(F)(F)C1)\C=C/CCN(C)C(=O)C[C@](O)(C(=O)NS(=O)(=O)N(C)C)c1ccc3OC[C@]4(CCCc5cc(Cl)ccc45)CN(C2)c3c1 |c:18|
Molecular Formula
C40H52ClF2N5O7S
Molecular Weight
820.39
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
MBS736108-01 48 Well
Chicken Anti-liver cytosol antibody type 1 ELISA Kit
Sign In for Pricing
View Details MBS736108-02 96 Well
Chicken Anti-liver cytosol antibody type 1 ELISA Kit
Sign In for Pricing
View Details MBS736108-03 5x 96 Well
Chicken Anti-liver cytosol antibody type 1 ELISA Kit
Sign In for Pricing
View Details MBS736108-04 10x 96 Well
Chicken Anti-liver cytosol antibody type 1 ELISA Kit
Sign In for Pricing
View Details 
K4730206 1.0 µg DNA
Aldh1b1 sgRNA CRISPR/Cas9 All-in-One Lentivector (Mouse) (Target 1)
Sign In for Pricing
View Details