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MBM-55

Product Specifications

CAS Number

2083622-09-5

Target

Apoptosis, Chk, Akt, GSK-3, DYRK, MAPK, Aurora Kinase, S6 Kinase, CDK, Bcr-Abl

Related Pathways

Chromatin/Epigenetic, PI3K/Akt/mTOR signaling, Apoptosis, Cell Cycle/Checkpoint, Tyrosine Kinase/Adaptors, Angiogenesis, Cytoskeletal Signaling, MAPK, Stem Cells

Purity

0.9998

Bioactivity

MBM-55 is an effective inhibitor of NIMA related kinase 2 (NEK2) with an IC50 of 1 nM. MBM-55 effectively inhibits the proliferation of cancer cells by inducing cell cycle arrest and apoptosis.

Smiles

CN(C)CCn1cc(cn1)-c1ccn2c(cnc2c1)-c1ccc(C(N)=O)c(OCc2cccc(F)c2)c1

Molecular Formula

C28H27FN6O2

Molecular Weight

498.55

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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