MBM-55
Product Specifications
CAS Number
2083622-09-5
Target
Apoptosis|||Chk|||Akt|||GSK-3|||DYRK|||MAPK|||Aurora Kinase|||S6 Kinase|||CDK|||Bcr-Abl
Related Pathways
Chromatin/Epigenetic|||PI3K/Akt/mTOR signaling|||Apoptosis|||Cell Cycle/Checkpoint|||Tyrosine Kinase/Adaptors|||Angiogenesis|||Cytoskeletal Signaling|||MAPK|||Stem Cells
Purity
0.9998
Bioactivity
MBM-55 is an effective inhibitor of NIMA related kinase 2 (NEK2) with an IC50 of 1 nM. MBM-55 effectively inhibits the proliferation of cancer cells by inducing cell cycle arrest and apoptosis.
Smiles
CN(C)CCn1cc(cn1)-c1ccn2c(cnc2c1)-c1ccc(C(N)=O)c(OCc2cccc(F)c2)c1
Molecular Formula
C28H27FN6O2
Molecular Weight
498.55
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
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