MBM-17
Product Specifications
CAS Number
2083621-90-1
Target
Aurora Kinase, MAPK, Apoptosis
Related Pathways
Chromatin/Epigenetic, Apoptosis, MAPK, Cell Cycle/Checkpoint
Bioactivity
MBM-17 is a potent inhibitor of NIMA-related kinase 2 (Nek2, IC50 of 3 nM) . It effectively inhibits the proliferation of cancer cells by inducing cell cycle arrest and apoptosis.
Smiles
O(CC1=CC=CC=C1)C=2C=C(C=3N4C(C=C(C=C4)C5=CN(CCN(C)C)N=C5)=NC3)C=CC2C(N)=O
Molecular Formula
C28H28N6O2
Molecular Weight
480.56
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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