Macitentan (n-butyl analogue)
Product Specifications
CAS Number
556797-16-1
Target
Others|||Endothelin Receptor
Related Pathways
GPCR/G Protein|||Others
Bioactivity
Macitentan n-butyl analogue, a derivative of Macitentan, functions as an orally active dual antagonist targeting both endothelin ETA and ETB receptors. This compound shows promise for treating idiopathic pulmonary fibrosis (IPF) and pulmonary arterial hypertension (PAH), leveraging its non-peptide structure for potential therapeutic applications.
Smiles
CCCCS(=O)(=O)Nc1ncnc(OCCOc2ncc(Br)cn2)c1-c1ccc(Br)cc1
Molecular Formula
C20H21Br2N5O4S
Molecular Weight
587.29
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
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