Macitentan-d4
Product Specifications
CAS Number
1258428-05-5
Target
Endothelin Receptor, Apoptosis
Related Pathways
GPCR/G Protein, Apoptosis
Purity
0.9651
Bioactivity
Macitentan-d4 (ACT-064992 D4) is a deuterated substitute for Macitentan and can be used as a dual antagonist of the non-peptides ETA and ETB (endothelin receptor) .Macitentan-d4 is less toxic than Macitentan, has a longer half-life, and can be used to study endothelin receptor-mediated diseases.
Smiles
N(S(NCCC)(=O)=O)C=1C(=C(OC(C(OC=2N=CC(Br)=CN2)([2H])[2H])([2H])[2H])N=CN1)C3=CC=C(Br)C=C3
Molecular Formula
C19H20Br2N6O4S
Molecular Weight
592.3
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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