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M‐89

Product Specifications

CAS Number

2363165-42-6

Target

Epigenetic Reader Domain, Histone Methyltransferase

Related Pathways

Chromatin/Epigenetic

Purity

0.9958

Bioactivity

M-89, a highly potent and specific inhibitor of the menin-mixed lineage leukemia (Menin-MLL) protein-protein interaction, exhibits a Kd of 1.4 nM for menin binding. This compound holds potential for treating MLL leukemia.

Smiles

CNC(=O)O[C@H]1CCC[C@@H]1[C@@]1(CN(C)Cc2ccccc12)C1CCN(CC2CN(C2)c2ccc(cc2)S(=O)(=O)c2ccncc2)CC1

Molecular Formula

C37H47N5O4S

Molecular Weight

657.87

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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