Lys-SMCC-DM1
Product Specifications
CAS Number
1281816-04-3
Target
Microtubule Associated|||Drug-Linker Conjugates for ADC
Related Pathways
Antibody-drug Conjugate/ADC Related|||Cytoskeletal Signaling
Purity
?98%
Bioactivity
Lys-SMCC-DM1 (Lys-N?-MCC-DM1) is an antibody-drug conjugate (ADC) targeting human epidermal growth factor receptor 2 (HER2) . It contains the microtubule polymerization inhibitor DM1 as the active metabolite, which inhibits microtubule polymerization. It is commonly used in breast cancer research.
Smiles
C[C@]12[C@@](O1)([C@H](C)[C@@]3(C[C@](O)([C@H](OC)/C=C/C=C(\C)/CC4=CC(N(C)C(=O)C[C@@H]2OC([C@@H](N(C(CCS[C@@H]5C(=O)N(C[C@@H]6CC[C@@H](C(NCCCC[C@@H](C(O)=O)N)=O)CC6)C(=O)C5)=O)C)C)=O)=C(Cl)C(OC)=C4)NC(=O)O3)[H])[H]
Molecular Formula
C53H75ClN6O15S
Molecular Weight
1103.71
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
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