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LY3020371 hydrochloride

Product Specifications

CAS Number

1377615-44-5

Target

GluR

Related Pathways

Neuroscience

Bioactivity

LY3020371 hydrochloride exerts an antidepressant-like signature in vivo. LY3020371 hydrochloride is a potent, selective metabotropic glutamate 2/3 receptor (mGlu2/3) antagonist with Ki of 5.3 and 2.5 nM, potently blocks cAMP formation with IC50 of 16.2 nM.

Smiles

Cl.[H][C@]12[C@H](C(O)=O)[C@@]1([H])[C@@](N)([C@H](CSc1ccc(F)c(F)c1)[C@H]2O)C(O)=O

Molecular Formula

C15H16ClF2NO5S

Molecular Weight

395.81

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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