LSN 3213128
Product Specifications
CAS Number
1941211-99-9
Target
Others, Antifolate
Related Pathways
Cell Cycle/Checkpoint, Others
Bioactivity
LSN 3213128, anti-tumor activity. is a selective, nonclassical, orally bioavailable antifolate with potent and specific inhibitory activity for aminoimidazole-4-carboxamide ribonucleotide formyltransferase (AICARFT), with IC50 of 16 nM for AICARFT enzyme inhibiton and 19 nM in cells.
Smiles
O[C@@H]1CCN(C1)c1ccc(s1)S(=O)(=O)Nc1cc2c(cc[nH]c2=O)cc1F
Molecular Formula
C17H16FN3O4S2
Molecular Weight
409.45
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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