LS-102
Product Specifications
CAS Number
1456891-34-1
Target
Ligand for E3 Ligase|||E1/E2/E3 Enzyme
Related Pathways
Ubiquitination|||PROTAC
Purity
0.9892
Bioactivity
LS-102 is a selective inhibitor of the E3 ligase synoviolin (Syvn1), an astragaloside IV derivative, which attenuates myocardial ischemia/reperfusion injury by inhibiting mitochondrial fission.LS-102 inhibits Syvn1 auto-ubiquitylation, which ameliorates amyloidazole-induced slowing of the heart rate, and is useful for studying cardiovascular diseases.
Smiles
CCNCCN(CC)c1nc(N[C@@H](C)C2CCCCC2)nc(Nc2ccc3ncoc3c2)n1
Molecular Formula
C24H36N8O
Molecular Weight
452.6
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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