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LS-102

Product Specifications

CAS Number

1456891-34-1

Target

Ligand for E3 Ligase|||E1/E2/E3 Enzyme

Related Pathways

Ubiquitination|||PROTAC

Purity

0.9892

Bioactivity

LS-102 is a selective inhibitor of the E3 ligase synoviolin (Syvn1), an astragaloside IV derivative, which attenuates myocardial ischemia/reperfusion injury by inhibiting mitochondrial fission.LS-102 inhibits Syvn1 auto-ubiquitylation, which ameliorates amyloidazole-induced slowing of the heart rate, and is useful for studying cardiovascular diseases.

Smiles

CCNCCN(CC)c1nc(N[C@@H](C)C2CCCCC2)nc(Nc2ccc3ncoc3c2)n1

Molecular Formula

C24H36N8O

Molecular Weight

452.6

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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