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Linaclotide

Product Specifications

CAS Number

851199-59-2

Target

Guanylate cyclase

Related Pathways

GPCR/G Protein

Purity

0.9871

Bioactivity

Linaclotide, developed for the treatment of constipation-predominant irritable bowel syndrome (IBS-C) and chronic constipation, is a potent and selective guanylate cyclase C agonist.

Smiles

C[C@@H](O)C1NC(=O)[C@@H]2CSSC[C@@H]3NC(=O)[C@@H](N)CSSC[C@H](NC(=O)[C@H](CSSC[C@H](NC(=O)CNC1=O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(O)=O)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](CCC(O)=O)NC3=O)C(=O)N[C@@H](CC(N)=O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C)C(=O)N2

Molecular Formula

C59H79N15O21S6

Molecular Weight

1526.74

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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