Leelamine hydrochloride
Product Specifications
CAS Number
16496-99-4
Target
Cannabinoid Receptor|||Androgen Receptor|||Fatty Acid Synthase|||Others
Related Pathways
Metabolism|||Others|||Endocrinology/Hormones|||GPCR/G Protein
Bioactivity
Leelamine hydrochloride, a tricyclic diterpene extracted from pine tree bark, inhibits the transcriptional activity of the androgen receptor, known to regulate fatty acid synthesis [2,3]. This compound acts as a cannabinoid receptor type 1 (CB1) agonist and suppresses SREBP1-regulated fatty acid/lipid synthesis in prostate cancer cells, irrespective of androgen receptor status.
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C[C@@]12C=3C(CC[C@]1([C@@](CN)(C)CCC2)[H])=CC(C(C)C)=CC3.Cl
Molecular Formula
C20H32ClN
Molecular Weight
321.93
Shipping Conditions
Cool pack
Storage Temperature
-20°C
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