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LCH-7749944

Product Specifications

CAS Number

796888-12-5

Target

PAK, Apoptosis

Related Pathways

Apoptosis, Cytoskeletal Signaling

Purity

0.9948

Bioactivity

LCH-7749944 (GNF-PF-2356) is a potent PAK4 inhibitor with an IC50 of 14.93 μM, effectively suppressing the proliferation of human gastric cancer cells by downregulating the PAK4/c-Src/EGFR/cyclin D1 pathway and inducing apoptosis.

Smiles

COc1cccc(Nc2nc(NCC3CCCO3)c3ccccc3n2)c1

Molecular Formula

C20H22N4O2

Molecular Weight

350.41

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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