LCH-7749944
Product Specifications
CAS Number
796888-12-5
Target
PAK|||Apoptosis
Related Pathways
Apoptosis|||Cytoskeletal Signaling
Purity
0.9948
Bioactivity
LCH-7749944 (GNF-PF-2356) is a potent PAK4 inhibitor with an IC50 of 14.93 ?M, effectively suppressing the proliferation of human gastric cancer cells by downregulating the PAK4/c-Src/EGFR/cyclin D1 pathway and inducing apoptosis.
Smiles
COc1cccc(Nc2nc(NCC3CCCO3)c3ccccc3n2)c1
Molecular Formula
C20H22N4O2
Molecular Weight
350.41
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
MBS9938310-01 48 Well
Monkey Probable G-Protein Coupled Receptor 146 (GPR146) ELISA Kit
Ask
View Details MBS9938310-02 96 Well
Monkey Probable G-Protein Coupled Receptor 146 (GPR146) ELISA Kit
Ask
View Details MBS9938310-03 5x 96 Well
Monkey Probable G-Protein Coupled Receptor 146 (GPR146) ELISA Kit
Ask
View Details 
MBS9938310-04 10x 96 Well
Monkey Probable G-Protein Coupled Receptor 146 (GPR146) ELISA Kit
Ask
View Details 