LCH-7749944
Product Specifications
CAS Number
796888-12-5
Target
PAK|||Apoptosis
Related Pathways
Apoptosis|||Cytoskeletal Signaling
Purity
0.9948
Bioactivity
LCH-7749944 (GNF-PF-2356) is a potent PAK4 inhibitor with an IC50 of 14.93 ?M, effectively suppressing the proliferation of human gastric cancer cells by downregulating the PAK4/c-Src/EGFR/cyclin D1 pathway and inducing apoptosis.
Smiles
COc1cccc(Nc2nc(NCC3CCCO3)c3ccccc3n2)c1
Molecular Formula
C20H22N4O2
Molecular Weight
350.41
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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MS4A6A, NT (CDA01, MS4A6, 4SPAN3, CD20L3, MST090, MSTP090, 4SPAN3.2, CDA01, Membranespanning 4-Domains Subfamily A Member 6A, CD20-like 3)
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