Laflunimus
Product Specifications
CAS Number
147076-36-6
Target
Dehydrogenase, Prostaglandin Receptor, DNA/RNA Synthesis
Related Pathways
Immunology/Inflammation, Metabolism, GPCR/G Protein, Cell Cycle/Checkpoint, DNA Damage/DNA Repair
Purity
0.9986
Bioactivity
Laflunimus (HR325) is a DHODH inhibitor that inhibits immunoglobulin IgM and IgG secretion in vitro and in vivo, with an IC50=2.5 μm, and exerts an immunosuppressive effect by interfering with pyrimidine metabolism, and is used in the study of neuralgia.
Smiles
N(C(/C(=C(\O)/C1CC1)/C#N)=O)C2=CC(C)=C(C(F)(F)F)C=C2
Molecular Formula
C15H13F3N2O2
Molecular Weight
310.27
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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