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L-803087

Product Specifications

CAS Number

217480-26-7

Target

Somatostatin

Related Pathways

GPCR/G Protein

Purity

0.9937

Bioactivity

L-803087 is a potent and selective agonist of the growth inhibitor sst4 receptor with a Ki value of 0.7 nM for sst4, demonstrating over 280-fold selectivity compared to other growth inhibitory receptors. L-803087 induces AMPA-mediated synaptic responses in the hippocampus in vitro and increases seizures in alginate-induced seizure-busting mice in vivo.

Smiles

COC(=O)[C@H](CCCNC(N)=N)NC(=O)CCCc1c([nH]c2c(F)cc(F)cc12)-c1ccccc1

Molecular Formula

C25H29F2N5O3

Molecular Weight

485.53

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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