L-803087
Product Specifications
CAS Number
217480-26-7
Target
Somatostatin
Related Pathways
GPCR/G Protein
Purity
0.9937
Bioactivity
L-803087 is a potent and selective agonist of the growth inhibitor sst4 receptor with a Ki value of 0.7 nM for sst4, demonstrating over 280-fold selectivity compared to other growth inhibitory receptors. L-803087 induces AMPA-mediated synaptic responses in the hippocampus in vitro and increases seizures in alginate-induced seizure-busting mice in vivo.
Smiles
COC(=O)[C@H](CCCNC(N)=N)NC(=O)CCCc1c([nH]c2c(F)cc(F)cc12)-c1ccccc1
Molecular Formula
C25H29F2N5O3
Molecular Weight
485.53
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
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