L-745870 hydrochloride
Product Specifications
CAS Number
1173023-36-3
Target
Dopamine Receptor
Related Pathways
GPCR/G Protein, Neuroscience
Purity
0.9958
Bioactivity
L-745870 hydrochloride has excellent brain penetration. L-745870 hydrochloride is a high-affinity, selective and orally active human dopamine D4 receptor antagonist with a Ki of 0.43 nM, and considerably weaker D2 receptor affinity with a Ki of 960 nM and D3 receptor affinity with a Ki of 2300 nM.
Smiles
Cl.Clc1ccc(cc1)N1CCN(Cc2c[nH]c3ncccc23)CC1
Molecular Formula
C18H20Cl2N4
Molecular Weight
363.28
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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