KY-05009
Product Specifications
CAS Number
1228280-29-2
Target
MAPK, Apoptosis, Wnt/beta-catenin
Related Pathways
Cytoskeletal Signaling, Stem Cells, MAPK, Apoptosis
Purity
0.9989
Bioactivity
KY-05009 is a chemical compound that effectively suppresses TGF-β1-induced epithelial-to-mesenchymal transition (EMT) in human lung adenocarcinoma cells, reduces TNIK protein expression and the transcriptional activity of Wnt target genes, and promotes apoptosis in cancer cells, displaying anti-cancer properties. Furthermore, it functions as an ATP-competitive Traf2- and Nck-interacting kinase (TNIK) inhibitor with a Ki of 100 nM.
Smiles
Cc1ccc(cc1)C(=O)Nc1sc(Nc2ccccc2)nc1C(N)=O
Molecular Formula
C18H16N4O2S
Molecular Weight
352.41
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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