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Eltanexor Z-isomer

Product Specifications

CAS Number

1642300-78-4

Target

CRM1, Others

Related Pathways

Membrane transporter/Ion channel, Others

Bioactivity

Eltanexor Z-isomer exhibits different inhibitory effects on Z138, MM15, 3T3 cell lines, with IC50s of 100 nM-50 μM, < 100 nM, > 30 μM, respectively.Eltanexor Z-isomer is the less active isomer of KPT-8602. KPT-8602 is a potent CRM1 inhibitor.

Smiles

NC(=O)C(=C/n1cnc(n1)-c1cc(cc(c1)C(F)(F)F)C(F)(F)F)\c1cncnc1

Molecular Formula

C17H10F6N6O

Molecular Weight

428.29

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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