Kira8
Product Specifications
CAS Number
1630086-20-2
Target
IRE1
Related Pathways
Cell Cycle/Checkpoint
Purity
0.9952
Bioactivity
Kira8 (AMG-18) is a mono-selective IRE1α inhibitor that allosterically attenuates IRE1α RNase activity with an IC50 of 5.9 nM.
Smiles
Cc1ccc2c(NS(=O)(=O)c3ccccc3Cl)cccc2c1Oc1ncccc1-c1ccnc(N[C@H]2CCCNC2)n1
Molecular Formula
C31H29ClN6O3S
Molecular Weight
601.12
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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