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KDOAM-25

Product Specifications

CAS Number

2230731-99-2

Target

Histone Demethylase, Antibacterial

Related Pathways

Microbiology/Virology, Chromatin/Epigenetic

Bioactivity

KDOAM-25, a potent and highly selective inhibitor of histone lysine demethylases 5 (KDM5) with IC50 values of 71 nM for KDM5A, 19 nM for KDM5B, 69 nM for KDM5C, and 69 nM for KDM5D, enhances global H3K4 methylation at transcriptional start sites and reduces proliferation in multiple myeloma MM1S cells.

Smiles

C(NCC(N(CCN(C)C)CC)=O)C1=CC(C(N)=O)=CC=N1

Molecular Formula

C15H25N5O2

Molecular Weight

307.39

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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