KDOAM-25
Product Specifications
CAS Number
2230731-99-2
Target
Histone Demethylase, Antibacterial
Related Pathways
Microbiology/Virology, Chromatin/Epigenetic
Bioactivity
KDOAM-25, a potent and highly selective inhibitor of histone lysine demethylases 5 (KDM5) with IC50 values of 71 nM for KDM5A, 19 nM for KDM5B, 69 nM for KDM5C, and 69 nM for KDM5D, enhances global H3K4 methylation at transcriptional start sites and reduces proliferation in multiple myeloma MM1S cells.
Smiles
C(NCC(N(CCN(C)C)CC)=O)C1=CC(C(N)=O)=CC=N1
Molecular Formula
C15H25N5O2
Molecular Weight
307.39
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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