JR-AB2-011
Product Specifications
CAS Number
2411853-34-2
Target
MTOR
Related Pathways
PI3K/Akt/mTOR signaling
Purity
0.9941
Bioactivity
JR-AB2-011 is a selective mTORC2 inhibitor with an IC50 value of 0.36 μM. It inhibits mTORC2 activity by blocking Rictor-mTOR association (Ki: 0.19 μM) and exhibits cytotoxicity in glioblastoma [1].
Smiles
CC1CN(C(=O)Nc2ccc(Cl)c(Cl)c2)\C(S1)=N\c1ccc(F)cc1
Molecular Formula
C17H14Cl2FN3OS
Molecular Weight
398.28
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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