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JR-AB2-011

Product Specifications

CAS Number

2411853-34-2

Target

MTOR

Related Pathways

PI3K/Akt/mTOR signaling

Purity

0.9941

Bioactivity

JR-AB2-011 is a selective mTORC2 inhibitor with an IC50 value of 0.36 μM. It inhibits mTORC2 activity by blocking Rictor-mTOR association (Ki: 0.19 μM) and exhibits cytotoxicity in glioblastoma [1].

Smiles

CC1CN(C(=O)Nc2ccc(Cl)c(Cl)c2)\C(S1)=N\c1ccc(F)cc1

Molecular Formula

C17H14Cl2FN3OS

Molecular Weight

398.28

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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