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JDTic Dihydrochloride

Product Specifications

CAS Number

785835-79-2

Target

Opioid Receptor

Related Pathways

GPCR/G Protein|||Endocrinology/Hormones|||Neuroscience

Bioactivity

JDTic Dihydrochloride is a high-affinity and selective ?-opioid receptor (KOR) antagonist that blocks dynorphin-KOR signalling, exhibiting antidepressant, anxiolytic, and anti-relapse effects against cocaine and nicotine.

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C[C@]1(C2=CC(O)=CC=C2)[C@H](CN(CC1)C[C@H](C(C)C)NC([C@H]3CC4=CC=C(O)C=C4CN3)=O)C.Cl.Cl

Molecular Formula

C28H41Cl2N3O3

Molecular Weight

538.55

Shipping Conditions

Cool pack

Storage Temperature

-20°C

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