JI051
Product Specifications
CAS Number
2234281-75-3
Target
Gamma-secretase
Related Pathways
Neuroscience, Stem Cells, Proteases/Proteasome
Purity
≥98.0%
Bioactivity
JI051 is an antitumor agent that interacts with the cancer-associated protein chaperone prohibitin 2 (PHB2) to induce cell cycle arrest by inhibiting the transcription of the Notch downstream effector gene, Hes1, and inhibits the proliferation of HEK293 cells and pancreatic cancer cells.
Smiles
CCOc1ccccc1CCNC(=O)\C=C\c1c[nH]c2c(OC)cccc12
Molecular Formula
C22H24N2O3
Molecular Weight
364.44
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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