JBJ-02-112-05

2748162-29-8

EGFR, JAK

JAK/STAT signaling, Tyrosine Kinase/Adaptors, Stem Cells, Chromatin/Epigenetic, Angiogenesis

JBJ-02-112-05 is a potent, mutant-selective, allosteric, and orally active inhibitor of EGFR, with an IC50 of 15 nM for EGFR L858R/T790M [1].

C(C(NC1=NC=CS1)=O)(N2C(=O)C=3C(C2)=CC=C(C3)C=4C=C5C(=CC4)NC=C5)C6=CC=CC=C6

C27H20N4O2S

464.54

Ice Packs

-20°C