JBJ-02-112-05
Product Specifications
CAS Number
2748162-29-8
Target
EGFR, JAK
Related Pathways
JAK/STAT signaling, Tyrosine Kinase/Adaptors, Stem Cells, Chromatin/Epigenetic, Angiogenesis
Bioactivity
JBJ-02-112-05 is a potent, mutant-selective, allosteric, and orally active inhibitor of EGFR, with an IC50 of 15 nM for EGFR L858R/T790M [1].
Smiles
C(C(NC1=NC=CS1)=O)(N2C(=O)C=3C(C2)=CC=C(C3)C=4C=C5C(=CC4)NC=C5)C6=CC=CC=C6
Molecular Formula
C27H20N4O2S
Molecular Weight
464.54
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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