Jasplakinolide
Product Specifications
CAS Number
102396-24-7
Target
Antifungal, Arp2/3 Complex, Microtubule Associated
Related Pathways
Microbiology/Virology, Cytoskeletal Signaling
Bioactivity
Jasplakinolide (Jaspamide), a naturally occurring cyclic peptide from marine sponges, is a potent inducer of actin polymerization.Jasplakinolide exhibits antifungal and antitumor activity and stabilizes pre-existing actin filaments. Jasplakinolide competitively binds to F-actin with the ghost pen cyclic peptide and has a Kd value of 15 nM for F-actin.
Smiles
C(C=1C=2C(NC1Br)=CC=CC2)[C@@H]3C(=O)N[C@H](CC(=O)O[C@@H](C)C[C@@H](C)\C=C(\C)/C[C@H](C)C(=O)N[C@@H](C)C(=O)N3C)C4=CC=C(O)C=C4
Molecular Formula
C36H45BrN4O6
Molecular Weight
709.67
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
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