Netoglitazone
Netoglitazone is a dual agonist of PPARα and PPARγ with antihyperglycemic activity[1].
Product Specifications
CAS Number
161600-01-7
Product Name Alternative
MCC-555; Isaglitazone
UNSPSC
12352005
Hazard Statement
H400, H410
Target
PPAR
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Metabolic Enzyme/Protease; Vitamin D Related/Nuclear Receptor
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/netoglitazone.html
Concentration
10mM
Purity
99.92
Solubility
DMSO : 250 mg/mL (ultrasonic)
Smiles
O=C(N1)SC(CC2=CC=C3C=C(OCC4=CC=CC=C4F)C=CC3=C2)C1=O
Molecular Formula
C21H16FNO3S
Molecular Weight
381.42
Precautions
H400, H410
References & Citations
[1]Reginato MJ, et al. A potent antidiabetic thiazolidinedione with unique peroxisome proliferator-activated receptor gamma-activating properties. J Biol Chem. 1998 Dec 4;273 (49) :32679-84.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Phase 2
Isoform
PPARα; PPARγ
Available Sizes
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