Itacitinib adipate
Product Specifications
CAS Number
1334302-63-4
Target
JAK|||Phosphatase
Related Pathways
Stem Cells|||JAK/STAT signaling|||Metabolism|||Chromatin/Epigenetic|||Tyrosine Kinase/Adaptors|||Angiogenesis
Bioactivity
Itacitinib adipate is an orally bioavailable and selective JAK1 inhibitor, tested for efficacy and safety in a phase II trial in myelofibrosis.
Smiles
N#CCC1(N2N=CC(=C2)C=3N=CN=C4NC=CC43)CN(C1)C5CCN(C(=O)C=6C=CN=C(C6F)C(F)(F)F)CC5.O=C(O)CCCCC(=O)O
Molecular Formula
C32H33F4N9O5
Molecular Weight
699.66
Shipping Conditions
Cool pack
Storage Temperature
-20°C
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