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Itacitinib adipate

Product Specifications

CAS Number

1334302-63-4

Target

JAK|||Phosphatase

Related Pathways

Stem Cells|||JAK/STAT signaling|||Metabolism|||Chromatin/Epigenetic|||Tyrosine Kinase/Adaptors|||Angiogenesis

Bioactivity

Itacitinib adipate is an orally bioavailable and selective JAK1 inhibitor, tested for efficacy and safety in a phase II trial in myelofibrosis.

Smiles

N#CCC1(N2N=CC(=C2)C=3N=CN=C4NC=CC43)CN(C1)C5CCN(C(=O)C=6C=CN=C(C6F)C(F)(F)F)CC5.O=C(O)CCCCC(=O)O

Molecular Formula

C32H33F4N9O5

Molecular Weight

699.66

Shipping Conditions

Cool pack

Storage Temperature

-20°C

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